EFFECT OF BIOLOGICAL SEX AND SHORT-TERM HIGH-FAT DIET ON CELLULAR PROLIFERATION, RIBOSOMAL BIOGENESIS, AND TARGETED PROTEIN ABUNDANCE IN MURINE ARTICULAR CARTILAGE

Effect of biological sex and short-term high-fat diet on cellular proliferation, ribosomal biogenesis, and targeted protein abundance in murine articular cartilage

Objective: To identify factors contributing to sex-differences in OA risk by evaluating the short-term effect of high-fat (HF) diet on sex-specific changes in cartilage cell proliferation, ribosomal biogenesis, and targeted extra-cellular and cellular protein abundance.Materials and methods: Knee cartilage was harvested to the subchondral bone from

read more